Editorial: Drug Re-purposing for the Treatment of Bacterial and Viral Infections
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چکیده
منابع مشابه
Pentamidine: a drug to consider re-purposing in the targeted treatment of multi-drug resistant bacterial infections?
© Journal of Laboratory and Precision Medicine. All rights reserved. J Lab Precis Med 2017;2:49 jlpm.amegroups.com The recent emergence of plasmid-mediated colistin resistance (1) highlights a new problem in the development of bacterial antimicrobial resistance. Colistin, while an old antibiotic, is increasingly turned to as a “drug of last resort” for many recalcitrant Gram-negative infections...
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Viral infections can cause of death in humans worldwide, despite the tremendous progress in human medicine. Particle size is a very important physical characteristic that can affect bioavailability and circulation time of nanoparticles. The ratio of large surface area and volume of nanoparticle enhanced solubility of poorly soluble drug compounds, optimum surface charge of the nanoparticle wi...
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Background: Despite the tremendous progress in human medicine, viral infections can cause death in them. Due to the high prevalence of viruses, it is required to develop novel treatment strategies and provide the site-specific delivery of antiviral agents at the viral reservoirs. Objectives: Particle size is a vital physical characteristic that can affect the bioavailability and circulation ti...
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Despite the advent of a considerable number of new antibiotics, treatment of intracellular pathogens still represents a major pharmaceutical challenge. The antibiotic concentration in those specialized niches are often subtherapeutic, for which high doses of antibiotics must often be used. This is not only costly but may also increase localized or systemic side effects. There is therefore an ur...
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ژورنال
عنوان ژورنال: Frontiers in Cellular and Infection Microbiology
سال: 2019
ISSN: 2235-2988
DOI: 10.3389/fcimb.2019.00387